France's Hollande bids to lock in campaign lead (AP)

LE BOURGET, France ? The Socialist candidate for France's presidency is attempting to consolidate his front-runner status on Sunday with the most high profile appearance of his campaign so far.

Observers say Francois Hollande, a bespectacled 57-year-old career politician, needs to inject a dose of dynamism into his campaign with the afternoon speech to an expected 10,000 people at an exhibition hall outside Paris.

Hollande plans to show French voters "where I come from, the meaning of my work over the past 20 years, and how I prepared to take on this responsibility," he told Le Monde newspaper in an interview published Saturday.

Hollande has extended his lead in polls over French President Nicolas Sarkozy, his expected rival in two-round elections in April and May. But he's virtually unknown outside France, and critics say he has limited international experience to head this nuclear-armed nation.

Hollande is an affable, soft-spoken and witty former longtime party boss who was chosen as the Socialist candidate in a primary last October.

He won the job after the most anticipated Socialist front-runner, Dominique Strauss-Kahn, had his is political career all but ended when he was jailed briefly in May in the United States after a New York hotel maid accused him of rape. Prosecutors later dropped the case, but Strauss-Kahn's reputation and presidential ambitions crashed.

Hollande has so far pitched his campaign on representing the anti-Sarkozy. When asked "Why you?" in an interview in October, Hollande first answered: "Because I can beat Nicolas Sarkozy."

He is known as good on the stump and a quick-witted debater, and has built his reputation as a manager and consensus-builder more than as a visionary.

He's never run a government ministry and during his tenure the party was weakened and badly fractured.

A lawmaker in the National Assembly and the governor of the central Correze region ? the same political backyard as conservative former President Jacques Chirac ? Hollande led the Socialist Party from 1997 to 2008.

During that time the Socialists suffered two devastating presidential campaign defeats, including the 2002 election when Prime Minister Lionel Jospin embarrassingly failed to qualify for the presidential runoff. Hollande's former partner Segolene Royal ? the mother of his four children ? was defeated by Sarkozy in the last presidential elections in 2007.

Hollande's program calls for reversing cuts in education introduced by Sarkozy's government, a new work contract to encourage companies to hire young people and focus on reducing France's high state budget deficit. It says little about international affairs, other than calling for an unspecified "pact" with Germany, the EU's economic engine, to spur on the now-troubled European project.

___

Greg Keller can be reached at http://twitter.com/Greg_Keller

Source: http://us.rd.yahoo.com/dailynews/rss/europe/*http%3A//news.yahoo.com/s/ap/20120122/ap_on_re_eu/eu_france_hollande

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More Evidence for Oxaliplatin as Colon Cancer Chemotherapy (HealthDay)

FRIDAY, Jan. 20 (HealthDay News) -- Adding oxaliplatin to a standard chemotherapy regimen boosts survival rates for patients with advanced colon cancer, according to a new study that bolsters previous research on the drug by looking at a broader group of patients.

"Physicians and patients should be reassured from our findings that oxaliplatin is associated with marginally but consistently superior survival for patients diagnosed before age 75 years in community settings," the study authors said in a news release.

In past studies, oxaliplatin, as an adjuvant to the established treatment of 5-fluorouracil (5-FU), improved survival by up to 23 percent. But the new study looked at a different group of colon cancer patients, who were older, sicker, more racially diverse and had never participated in a controlled clinical study.

The study, led by Dr. Hanna Sanoff, an assistant professor of medicine, hematology and oncology at the University of Virginia School of Medicine, appears in the Jan. 20 issue of the Journal of the National Cancer Institute.

Colon cancer is one of the world's deadliest diseases, with more than 100,000 Americans diagnosed last year, the researchers noted. Of these, roughly a third had an advanced -- stage 3 -- cancer, for which surgery is the principal treatment.

Surgery alone produces disease-free survival rates of between 15 percent and 50 percent five years following treatment, according to study background information. To improve their chances, patients often also undergo post-surgical chemotherapy.

Up until 2004, the drug 5-FU -- given in combination with leucovorin, which boosts its effects -- was the chemotherapy of choice for colon cancer, sparking a 26 percent drop in death rates compared to patients undergoing surgery alone.

But in 2004, several U.S. National Cancer Institute studies indicated that by adding oxaliplatin to the 5-FU mix, patients could see survival rates rise by yet another 23 percent.

The one caveat: Only a tiny slice of cancer patients (less than 2 percent) participated in those clinical trials, and those tended to be younger, healthier and less diverse than the larger general population of colon cancer patients.

To determine whether oxaliplatin would show a similar benefit among a "real-world" population of patients, the authors sifted through five cancer registries containing survival information on more than 4,000 people with stage 3 colon cancer. All were younger than 75, and all had begun chemotherapy -- either a standard regimen or in combination with oxaliplatin -- within four months of having surgery between 2004 and 2009.

Researchers compared their survival rates with those of nearly 8,300 patients who had participated in one of five different clinical trials using oxaliplatin.

The addition of oxaliplatin to standard chemotherapy protocols was found to be just as effective in prolonging survival among the community-based set of patients -- including the elderly, minorities and those with additional complicating health issues -- who were not enrolled in studies.

For her part, Dr. Felice Schnoll-Sussman, a gastroenterologist at New York-Presbyterian Hospital/Weill Cornell Medical Center in New York City, said the finding "goes along with what we've previously known."

"So, it's not surprising," she said. "But, certainly this is positive. The analysis doesn't focus on some of the most common adverse reactions seen with this combination. But in terms of survival, it certainly supports our previously held belief that oxaliplatin increases survival and lowers the chance of cancer returning in some of those stage 3 post-surgery patients."

More information

For more on colon cancer, visit the U.S. National Library of Medicine.

Source: http://us.rd.yahoo.com/dailynews/rss/health/*http%3A//news.yahoo.com/s/hsn/20120120/hl_hsn/moreevidenceforoxaliplatinascoloncancerchemotherapy

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Windows Phone overtakes Apple iOS by 2015?

Nokia USA

Nokia Lumia 900 in "Cyan."

By Athima Chansanchai

Nokia is not only pinning its hopes for renewed relevancy with its first 4G LTE Windows Phone, the Lumia 900, it could also break the smartphone operating system deadlock and propel Windows Phone ahead of iOS.

Market researchers at IHS have published a report that predicts the usurping of Apple's iOS by Windows Phone in 2015 by a slight margin, leaving Android with a more-than-comfortable lead at No.1.

(This, despite a recent Nielsen survey that shows Apple closing in on Android, with more smartphone buyers choosing iOS in recent purchases.)?

IHS reports that in three years, "Windows Phone will account for 16.7 percent of the smartphones shipped, up from less than 2 percent in 2011."

(Msnbc.com is a joint venture of Microsoft and NBC Universal.)

Here's a table illustrating their analysis:

IHS

Wayne Lam, who wrote the IHS release, is a fan of the new phone, and sees it as the key toward turning things around for Nokia.

"This hot product represents Nokia's first step to reclaim its market share. Combined with Nokia's efforts to drive the development of the Windows Phone ecosystem, the Lumia 900 and its successors will help Microsoft to reclaim its No. 2 ranking in smartphone operating system market share in 2015."

It's an attractive device that Nokia debuted at the recent Consumer Electronics Show in Las Vegas. In a diminutive frame, the phone has a?4.3-inch AMOLED touch screen, a 12-megapixel camera with Carl Zeiss optics (an F2.2 aperture lens with a 28mm focal length) and front-facing camera for video chats and a?long-lasting 1830 mAH battery.

As with other Windows Phones, it features the "People Hub," which connects the phone's owner with friends in real-time updates with "Live Tiles." Nokia has partnered with major carriers in North America, including?Rogers and Telus; and in the U.S., AT&T.

Lam sees the Lumia 900 as an almost messianic device to trigger Nokia's dominance within the Windows Phone arena, too:

Although Nokia is not the only seller of Windows Phone smartphones, the company is expected to dominate the market, accounting for 50 percent of all Microsoft OS-based handsets sold in 2012, IHS predicts. The company?s share then is set to rise to 62 percent in 2013. Nokia's portion of the market will begin to decline in 2014, as other companies increase their sales of Windows Phone products.

Nokia is also hoping to make inroads with the new-to-the-smartphone crowd through T-Mobile and its Lumia 710 ??which I'm not yet convinced is right for first-timers like my dad, who have never touched a touch screen before, much less a smartphone, but I am willing to spend more time with it (so you'll read about that in due time, Windows Phone fanboys). That phone has been priced to sell to the masses, costing nothing at Walmart (with a two-year contract) and only a penny at Costco.

More stories:

Check out Technolog on?Facebook, and on Twitter, follow?Athima Chansanchai, who is also trying to keep her head above water in the?Google+?stream.

Source: http://technolog.msnbc.msn.com/_news/2012/01/19/10191041-windows-phone-overtakes-apple-ios-by-2015

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Newt Gingrich Posts Income Tax Return on the Internet During Debate (Mashable)

As a debate began between the Republican presidential candidates, Newt Gingrich released his 2010 federal income tax return, placing it on the Internet for all to see. In an obvious political ploy to goad his opponent Mitt Romney into revealing his income tax returns, Newt Gingrich's campaign released the tax return along with a statement:

[More from Mashable: Newt Gingrich Attacked By Digital Vandals]

"Speaker and Mrs. Gingrich owed federal taxes of $994,708 on an adjusted gross income of $3,142,066. $613,517 of the tax amount owed had been previously withheld or otherwise paid, and the couple paid the remaining balance due of $382,734 (which included an estimated $1,543 tax penalty) with their filing."

"Included in the wage and salary income reported on Speaker and Mrs. Gingrich?s tax return is $450,245 in combined wages; $41,625 in income from speaking and board of directors fees; $6,853 in rental income from real estate holdings; $11,892 in ordinary dividends; $5,990 in qualified dividends; and $2,525,683 in income from partnerships and S corporations, including the Lubbers Agency Inc. and Gingrich Holdings, Inc.

[More from Mashable: This Week in Politics & Digital: Debt to Pay]

"For the year 2010, the Speaker and Mrs. Gingrich reported $4,184 in net short-term capital gains and $32,541 in net long-term capital losses. Over the course of the year, the couple also contributed $81,133 to various charities, including the Basilica of the National Shrine of the Immaculate Conception."

For a peek inside the personal financial dealings of someone who is obviously quite wealthy, take a look at Newt Gingrich's tax return here (.pdf file). Gingrich's financial disclosure forms filed last summer revealed he's worth more than $6.7 million.

Image courtesy of Gage Skidmore, Flickr

This story originally published on Mashable here.

Source: http://us.rd.yahoo.com/dailynews/rss/internet/*http%3A//news.yahoo.com/s/mashable/20120119/tc_mashable/newt_gingrich_posts_income_tax_return_on_the_internet_during_debate

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